Rosetta Virtual Workshop – August 2-6th 2021
Workshop materials will be in the morning (US Central Time) on each of Aug 2-4th. They’ll consist of both video lectures, as well as a link to downloadable materials to complete the tutorial on your own machine.
The tutorials are structured as self-paced exercises, so feel free to work on the tutorials and videos at your own pace, as your schedule permits.
Instructors will be availible during standard US Central Time hours Aug 2-6th to registered participants on the Discord server to answer questions about the materials.
Workshop Materials:
Youtube Playlist of all workshop presentations. (Note that some are re-used from the 2020 Workshop.)
Self-paced instructions for the tutorials can be found within the zip file, as plain text (.md), webpage (.html) or PDF (.pdf) format.
Introduction:
- Preparation
- Computer-Aided Design of Antibodies and Vaccines (video)
- Introduction to Antibody Structural Biology (video)
Main Topics:
Tutorial 1: Antibody Structure Prediction
Tutorial 2: Antibody-Antigen Docking (Protein-Protein Docking)
Tutorial 3: Computational Affinity Maturation
- Overview (video)
- Single State Design Instructions (pdf)
- Multistate Design Instructions (pdf)
- Materials (zip)
- Walkthrough (video)
Tutorial 4: Rosetta Antibody Design
Tutorial 5: Motif Grafting and Scaffolding
- Overview (video)
- Additional Protocols (video)
- Instructions (pdf)
- Materials (zip)
- Walkthrough (video)
Tutorial 6: Glycan Modeling and Epitope Blocking
- Introduction (video)
- Glycans in Rosetta (video)
- Instructions (pdf)
- Materials (zip)
- Walkthrough (video)