About The Meiler Lab

The Meiler Lab is uniquely located both in the United States and Germany, and is actively involved in developing the Rosetta computational modeling software suite together with 15 other laboratories in the United States. As an integral part of the Rosetta community, the Meiler lab works to better understand macromolecular interactions, design custom molecules, and develop efficient ways to search conformational and sequence space.


To enable protein structure elucidation of membrane proteins the primary target of most therapeutics and large macromolecular complexes such as viruses.


Design proteins with novel structure and/or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.


Understand the relation between chemical structure and biological activity quantitatively in order to design more efficient and more specific drugs.


Antibodies, Vaccines and Immunity

"Meiler Lab is expert in the field of structure-based reverse vaccinology. Starting from co-crystal structures of antigens and antibodies..."More DetailsCreative Solutions

Small Molecules

“Small molecules” is a wage term for all organic molecules with a molecular mass smaller than 600-800 Da. The term “small molecule…"More DetailsFinanancial Strategy

Membrane Proteins

"Membrane proteins play important roles in many biological pathways. Understanding membrane proteins may require an..."More DetailsKeyword Research

Protein Discovery and Design

"Rational protein design generates new protein macromolecules with novel functions, increased therapeutic efficacy, and novel fold patterns..."More DetailsMarketing Strategy

Personalized Structural Biology

"Personalized Structural Biology Medicine has experienced a revolution in the methods used to diagnose and treat disease. Dramatic..."More DetailsWeb Development

Diseases we cure

"Viral Infections, Cancer, Neurodegenerative diseases, many others diseases are worked on in the Meiler Lab..."More DetailsRestructuring

Recent News

Aodong Liu received the Thomas W. Martin Award!

The Thomas W. Martin Award was established in 1993 in memory of Thomas W. Martin, professor of chemistry at...

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Tiffany Alyssa Shields received the Merck Index Award!

The Merck Index Award is awarded annually to an outstanding graduating senior who is going on to medical school...

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Taylor Jones received the Biomedical Informatics T15 Training Grant...

Taylor Jones will join Meiler Lab as a graduate student starting from June 1st 2020! The training grant appointment...

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Eli McDonald received the Dissertation Enhancement Grant from the...

Eli McDonald has been awarded a Russell G. Hamilton Graduate Leadership Institute Dissertation Enhancement Grant! The Graduate Leadership Institute...

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