Select a format for your variants input.
VCF is a tab-delimited format. Your GRCh37 file will be first “lifted over” to GRCh38 with the UCSF tool. Then, it will be filtered for missense variants using the Ensembl VEP Your VCF file tab-delimited headers should be minimally:
#CHROM POS ID REF ALT
Paste a comma delimited set of data…