Cystic Fibrosis
Cystic Fibrosis (CF) is a common lethal, genetic disease caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), an epithelial anion channel in several vital organs. ...
Retinitis Pigmentosa
Retinitis pigmentosa (RP) is a genetic disorder that results in night blindness, loss of peripheral vision, and in severe cases complete blindness. RP can be caused by mutations in many different genes. ...
Diabetes & Obesity
The Meiler Lab has long-standing collaborations with researchers and clinicians in the field of diabetes and obesity to identify genetic variants of concern for these disorders and investigates structural changes ...
Chronic Kidney Disease
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Platelet Aggregation
Cardiovascular diseases continue to be among the most prominent life-threatening diseases, many of which are linked to thrombotic events. There exist a number of available medications to prevent thrombosis in cardiovascular diseases ...
Acute Kidney Injury
Acute kidney injury (AKI) is defined as an abrupt decrease in renal function. The reported incidence of AKI varies from 5% in all hospitalized patients to 30% to 50% in intensive care units. Incomplete recovery from AKI leads to chronic ...