MusiteDeep (PTMs) within 8.0A of G570

PTM Residue	PTM Type	Probability
567	Ubiquitination	0.6
621	Phosphoserine	0.6

Structure Summary

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
swiss	Q9NZ71-7_3_780_7o75.1.A	A	7o75.1.A		26.32	1.0			3	780			0.16	0.518	-0.01	0.264
modbase	ENSP00000424307.2_1	A	4a15		21.0	1.0			21	771			0.49	0.546	-0.01	0.207

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
swiss	Q9NZ71-7_3_780_7o75.1.A	A	7o75.1.A		26.32	1.0			3	780			0.16	0.518	-0.01	0.264

clinvar Results - Q9NZ71-7_3_780_7o75.1.A.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
2.52	5.00	2.02	12.00	0.73	0.52	0.16	0.99	0.06

COSMIC Results - Q9NZ71-7_3_780_7o75.1.A.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
1.77	8.00	-1.02	9.00	0.47	0.26	-0.01	1.00	0.00

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
modbase	ENSP00000424307.2_1	A	4a15		21.0	1.0			21	771			0.49	0.546	-0.01	0.207

clinvar Results - ENSP00000424307.2_1.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
2.06	8.00	1.68	20.00	0.71	0.55	0.49	0.98	0.19

COSMIC Results - ENSP00000424307.2_1.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
2.00	9.00	-1.67	10.00	0.40	0.21	-0.01	1.00	0.00