MusiteDeep (PTMs) within 8.0A of G323

PTM Residue	PTM Type	Probability
320	Ubiquitination	0.6

Structure Summary

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
swiss	Q9NZ71-9_226_533_7o75.1.A	A	7o75.1.A		25.76	1.0			226	533			0.23	0.59	-0.02	0.184
modbase	ENSP00000322287.5_1	A	3crw		30.0	1.0			244	492			0.35	0.87	0.01	0.185

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
swiss	Q9NZ71-9_226_533_7o75.1.A	A	7o75.1.A		25.76	1.0			226	533			0.23	0.59	-0.02	0.184

clinvar Results - Q9NZ71-9_226_533_7o75.1.A.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
-2.80	27.00	1.59	12.00	0.69	0.59	0.23	0.98	0.10

COSMIC Results - Q9NZ71-9_226_533_7o75.1.A.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
-2.67	31.00	-1.19	9.00	0.34	0.18	-0.02	0.99	0.00

Method	Structure Id	Chain	PDB Template	PDB Resolution	Template Identity	Transcript Identity	AF Global Quality	AF Residue Confidence	Seq Start	Seq End	ddG Monomer	ddG Cartesian	Pathprox clinvar	Pathprox clinvar AOC	Pathprox COSMIC	Pathprox COSMIC AOC	PDB Pos
modbase	ENSP00000322287.5_1	A	3crw		30.0	1.0			244	492			0.35	0.87	0.01	0.185

clinvar Results - ENSP00000322287.5_1.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
-2.26	45.00	-1.09	42.00	0.88	0.87	0.35	0.78	0.33

COSMIC Results - ENSP00000322287.5_1.A

Neutral Kz	Neutral Kt	Pathogenic Kz	Pathogenic Kt	ROC AUC	PR AUC	PathProx	Neutral Constraint	Pathogenic Constraint
-1.54	32.00	-2.54	28.00	0.27	0.19	0.01	0.86	0.14